Physiological age related changes in skin are most pronounced in fair persons than blacks. The major stigma of aging in the skin is wrinkling, roughness, pigmentation and cancers. Skin is composed of epidermis and dermis. Outer epidermis is dead layer of stratum corneum while the inner one is viable layer composed of keratinocytes, melanocytes and Lagerhan’s cells. Dermis is composed of collagen. Loss of elastin and collagen is a contributory factor for wrinkling. Dermal thickness is reduced to more than 20% with age. The moisture content of the aged skin is less than adult skin. Regression and disorganization of blood vessels is one of prominent feature of aging. Cutaneous sensation is reduced lesser than tactile sensitivity by the age of 80 -85 years.
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