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Tuesday, November 23, 2010

Tramadol

Tramadol is weak synthetic opioid analgesic than morphine which acts selectively upon mu receptors.It has low dependence liability and does not produce significant respiratory depression. Toxic doses can produce convulsions and even cause excitement. Analgesic effect if aspirin is enhanced when tramadol is combined with it.Oral absorption of tramadol is higher with bioavailability being 50%. Addiction to tramadol is much less than codeine hence it is mostly used now-a-days. Dizziness, nausea and sedation are few adverse effects of the drug.

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